OSU researchers compared mice against a related pilot study in humans and its showing how regular activity and stress reduction could lead to better health in the long run for lupus sufferers.
In the mouse model of lupus, researchers from found that moderate exercise significantly decreased inflammatory damage to the kidneys. While 88 percent of non-exercised mice had severe damage, only 45 percent of the treadmill-exercised animals did.
Researchers believe several biomarkers known to drive inflammation plummeted in the exercise group. Previous studies have supported the idea that physical activity is good for lupus patients, but hard scientific evidence explaining why has been scarce.
Researchers hope to change that through their work and help lupus sufferers relieve some of their pain through this new information on the benefits of exercise and lupus related inflammation.
OSU researchers have been looking at the well-established link between obesity and chronic pain. The link between the two, researchers found, could well be inflammation and the study points to the anti-inflammatory benefits of foods like fish, nuts and beans. Lead researcher, Charles Emery, professor of psychology at OSU, thinks a Mediterranean diet could be a key to preventing or reducing inflammatory pain in obese patients.
After developing their research model – which would determine whether components of an anti-inflammatory diet high in veggies, fruits, healthy fats and whole grains might play a key role in whether weight might lead to pain – researchers found a clear pattern existed. Eating a such a diet reduced body pain regardless of body weight.
The study also upheld previous research showing that people who are overweight or obese are more likely to experience pain. It included 98 men and women 20 to 78 years old and appears this month in the journal Pain.
While changes in diet to produce medical results should always be discussed with one’s primary care physician, this research could be a great way for some chronic pain sufferers to begin a path towards healing. The Mediterranean diet has already proven itself on the battlefield of heart health and weight loss, and now may earn a gold star rating in the realm of pain management.
Women with the least-inflammatory diets (based on a scoring system called the Dietary Inflammatory Index) lost less bone density during the six-year follow-up period than their peers with the most-inflammatory diets. This was despite the fact that they started off with lower bone density overall.
Furthermore, diets with low inflammatory potential appeared to correspond to lower risk of hip fracture among one subgroup of the study – post-menopausal white women younger than 63.
Researchers examined data from the landmark Women’s Health Initiative to compare levels of inflammatory elements in the diet to bone mineral density and fractures and found new associations between food and bone health. The study, led by Tonya Orchard, an assistant professor of human nutrition at The Ohio State University, appears in the Journal of Bone and Mineral Research.
The findings suggest that women’s bone health could benefit when they choose a diet higher in beneficial fats, plants and whole grains, said Orchard, who is part of Ohio State’s Food Innovation Center.
However, because the study was observational, it’s not possible to definitively link dietary patterns and bone health and fracture outcomes.